Centering on air-sea interface, sea-land interface, and seabed interface, efforts will be made to focus on ocean and climate, health of ecological system, changes of biological resources, land-sea interaction, deep earth processes, subsurface biosphere, and other key science issues. From the perspective of earth system, frontier, comprehensive and interdisciplinary research in the air, waters, biology, rock, and other circles of Indo-Pacific convergence region will be conducted. An integrated observation system spanning air, sea, and land will be built, cutting-edge technologies in deep sea will be developed, and research will be pursued to develop high-performance earth system model, so as to provide technique support to national marine environment safety, climate prediction and forecast, the utilization of marine resources, the Belt and Road Initiative, and other major national programs.